“Now, more than ever, our focus is on products that have strong entry barriers including biosimilars, inhalation and complex injectables. We believe this focus will help us overcome structural changes in key markets like the US,” said Lupin's managing director Nilesh Gupta in a statement.
A thrust in complex and specialty portfolios, it is felt, will give Indian drug makers
a competitive edge in the US market. This is even more crucial now, due to consolidation in the distribution channel and entry of about 50 new generic drug makers
in the US in a year. Multinational pharma companies like Novartis and Teva too are re-setting their pharma businesses as challenges mount in the US. While Novartis is looking to sell its generic drugs
business in the US, while Teva is implementing a $3-billion cost-saving plan.
Pharma majors are evaluating their generic drug pipeline in the US in view of challenges like price erosion and customer consolidation
Companies are focussing on developing speciality products
Research and development strategy is geared towards limited products and limited competition products
Sun Pharma has withdrawn around 15 product applications in view of changed market conditionsCadila Healthcare has said its portfolio will have a mix of both high-volume generic drugs and speciality products
“We are relooking at part of our generic R&D,” Sun Pharma managing director Dilip Shanghvi told analysts in a post-result conference call last week. Sun Pharma, which is building a pipeline of specialty products in ophthalmic, oncology and dermatology in the US, also has also withdrawn over 15 product filings over the past six months in view of changed market conditions.
“Glenmark is focusing on limited launches and limited competition products,” a company spokesperson said. “Our strategy has always been about filing 15-20 products every year, and this will remain unchanged. However the nature of the filings will very different from what we have done in the past.”
Last year Glenmark spent some Rs 12.62 billion on R&D, or 14-15 per cent of its sales (excluding cholesterol drug Zetia). In FY2018, the R&D spend in absolute terms will be significantly lower than last year, the company said.
Ahmedabad-based Cadila Healthcare's US product pipeline will include a mix of both large-volume generics and specialty products, said managing director Sharvil Patel. The company believes there is an opportunity in developing high-volume drugs given periodic supply disruptions in the market.
“I believe in having large-volume products and obviously differentiated niche products. We have a development pipeline of around 150 products, including complex ones. We are putting lot of effort in developing specialty products and we will launch one this year. That will be a key focus. We are also looking for partners for in-licensing technologies,” Patel said.
The exception in the pack is Aurobindo Pharmaceuticals, which is building a large basket of drugs in multiple-dosage formats. Sources familiar with the company's strategy say it isn't reducing its plain vanilla generic drug filings but is parallelly focusing on complex products such as injectables, peptides, and hormones in the US. Aurobindo does not sell finished dosages in India and earns over 70 per cent of its sales in the US and Europe. That is one reason for large number of filings in the markets.