Hydroxychloroquine (HCQ) is a medication used to prevent and treat malaria. Other uses include treatment of rheumatoid arthritis and lupus erythematosus. It is also being studied as an experimental treatment for Covid-19.
On March 28, 2020, the Food and Drug Administration (FDA) gave an emergency approval to the US government to distribute millions of doses of anti-malarial drugs to hospitals across the country, saying it is worth the risk of trying unproven treatments to slow the progression of the disease caused by the novel coronavirus
in seriously ill patients. However, FDA’s emergency authorization does not cover longer-term use of the drugs to prevent the coronavirus infection.
What experts say on the use of hydroxychloroquine for Covid-19 patients
Top US infectious disease expert Dr Anthony Fauci, in an interview with CNN said,"I would have two words for you: 'second opinion.' Hydroxychloroquine is officially approved for treating malaria, rheumatoid arthritis and lupus, but not Covid-19." Fauci said more testing is needed before it's clear that the drug works against the coronavirus and is safe for COVID-19 patients. Health
experts also warn the drugs’ well-known side effects could become commonplace with wide use. In particular, they say, patients with existing heart problems or taking certain drugs, such as anti-depressants that affect heart rhythm, are at risk of a fatal episode. Experts recommend screening before the drugs are prescribed to prevent drug-related deaths.
Demand for hydroxychloroquine
Hydroxychloroquine is an inexpensive and easily available drug. However, its demand has risen dramatically ever since it was named as a possible treatment for Covid-19. India manufactures it in large quantities. On Saturday, the government banned the export of the drug "without any exception". The order came even as the number of positive cases of Covid-19 spiked in the country.
On Tuesday, however, the government partially lifted the ban, paving the way for its supply to the US and several other countries hit hard by the coronavirus pandemic.
Government officials said India would export hydroxychloroquine and paracetamol on a case-by-case basis to the countries which have already placed orders for them after meeting the domestic requirements.
The decision to partially lift the ban on hydroxychloroquine came to the fore hours after US President Donald Trump warned of retaliation if India does not heed to his request to supply the drug, cited by him as a viable therapeutic solution to fight coronavirus infection.
According to news
agency PTI, India is said to have received requests from at least 20 countries including its immediate neighbours Sri Lanka and Nepal for supply of hydroxychloroquine.
When was this drug first approved
Hydroxychloroquine was approved for medical use in the United States in 1955. It is on the World Health
Organization's List of Essential Medicines, the safest and most effective medicines needed in a health
What are side effects of hydroxychloroquine?
Common side effects include vomiting, headache, blurry-vision, and muscle weakness, according to health experts. Severe side effects may include allergic reactions.
For most people, the virus causes mild or moderate symptoms, such as fever and cough that clear up in two to three weeks. For some, especially older adults and people with existing health problems, it can cause more severe illness, including pneumonia, and death. So far, nearly 75,000 people across the globe have died from the disease.