"The very, very rich got very, very richer," said Forbes' Chief Content Officer Randall Lane, in an interview with Reuters Video News.
Tesla Chief Executive Elon Musk jumped into second spot on the list, up from 31st last year.
Bernard Arnault, chief executive of luxury goods firm LVMH, Microsoft founder Bill Gates and Facebook Chief Executive Mark Zuckerberg round out the top five of the world's richest billionaires.
Investor and business tycoon Warren Buffett fell out of the top five for the first time in over two decades, as tech executives dominate the Forbes rankings.
With an estimated net worth of $84.5 billion, Reliance Industries' chairman Mukesh Ambani, Asia’s richest man, is ranked at number 10.
He surged ahead of Jack Ma of China, Asia’s richest person a year ago, whose rank dropped to 26 despite a near $10-billion jump in his fortune at $48.4 billion.
Gautam Adani is the second richest Indian in the Forbes list.
Forbes used stock prices and exchange rates from March 5 to calculate net worths.
This year's list has 493 newcomers, including Whitney Wolfe Herd, chief executive of dating app Bumble, which went public this year.
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