In August 2017, it was confirmed that Kulsoom was suffering from lymphoma (throat) cancer and was shifted to London for further treatment. On June 15, she was placed on a ventilator following a cardiac arrest.
She served as Pakistan's first lady for three non-consecutive terms from 1990-1993, 1997-1999 and 2013-2017, The Dawn reported.
Kulsoom is survived by her husband and four children - Maryam, Hassan, Hussain and Asma. Her husband and daughter are presently serving jail terms after being convicted for corruption.