Ami Modi is stated to have left country soon after the alleged bank fraud case came into light in 2018.
The ED has charged Ami Modi for conspiring and money laundering with her husband and jeweller Nirav Modi apart from his uncle Mehul Choksi and others under the Prevention of Money Laundering Act (PMLA).
Nirav Modi (49), is currently lodged in a UK jail after being arrested in London in March, 2019 and is currently fighting extradition to India.
He has been declared a fugitive economic offender by a Mumbai court early this year and the court had also ordered confiscation of his assets.
The ED has already confiscated about Rs 329 crore of his linked properties.
The businessman, Choksi and others are being probed by the ED on money laundering charges in connection with an over $2 billion alleged bank fraud at a PNB branch in Mumbai.
Similar Interpol notices have been earlier been issued against Nirav Modi's younger brother Nehal Modi and sister Purvi Modi.