A local police official said the car driver was apparently trying to overtake another vehicle and rammed into the truck.
One more person who was travelling in the car sustained minor injuries, he said. His identity was not known yet.
Azmi's spokesperson said the actor was undergoing a check-up. "She is fine, nothing to worry about," the spokesperson added.
Javed Akhtar celebrated his 75th birthday on Friday.
Azmi is known for her path-breaking roles in films such as "Arth", "Ankur", "Paar", "Masoom" and "Godmother".